ElastinAlthough elastin is widely distributed in the human body, as much as collagen, and is a key component necessary for the elasticity of all parts of the body, such as skin, blood vessels, muscles, ligaments, and joints, research has not been conducted much compared to collagen.
Many signs of aging are related to human elasticity, such as decreased elasticity in the skin, high blood pressure due to decreased vascular elasticity, less mobility due to decreased muscle and ligament elasticity.
Body elasticity changes including all these aging symptoms are closely related to the aging and degeneration of elastic fiber and elastin.
Elastic Lab is researching and developing the technology to improve the aging of Elastic fibers and elastin so that mankind can prepare for the “centenarian age” with more activity and elasticity.
What is Elastin?
Elasticity Research, The Core of Human Elasticity is Elastin.Elasin is a key protein responsible for the elasticity of elastic fibers located in the ECM (extracellular matrix), it plays a role in restoring the human tissues such as skin, blood vessels, lungs, and ligaments to their original shape when pinched or stretched.
Elastin is involved in the regulation of various cellular processes such as promoting actin fiber and arterial formation, inhibiting smooth muscle cell proliferation, regulating cell migration, inducing chemotaxis of monocytes and etc.
What is ECM
ECM is a three-dimensional structure consisting of Elastin, Hyaluronic Acid and Collagen that supports the structure and biochemical reactions of surrounding cells.
Physical Role : Support and bonding of tissue, physical boundaries, absorption of forces, elastic elements
Physiochemical Role : Cell proliferation, cell migration, intracellular metabolism, cell differentiation, cell morphology and etc. are regulated from outside the cell
ECM AgingAs the skin ages, the quantity and quality of major components such as Elastin and Collagen decrease, which decreases skin elasticity and increases wrinkle. Therefore, aging skin care should be focused on all the components of the skin.
|Elastin: Maintain skin elasticity|
|Collagen: Maintain skin structure|
|Hyaluronic Acid: Maintain skin moisture|
Elastin AgingDuring ageing, elastin is subject to remodelling and fragmentation. Different factors can contribute to elastin fragility and rupture such as mechanical fracture, calcification, glycation, carbamylation, and peroxydation. In addition, these factors enhance elastin susceptibility to proteolysis by specific elastases such as serine, cysteine, and matrix-metalloproteinases.
Patent Applied Composition
- Increase intracellular expression of Elastin(ELN) and Collagen Type I (COL1A2) genes
- Increase extracellular synthesis of Elastin and Collagen proteins
Development of Composition Inducing Elastin & Collagen Genes and Protein Expression
- Elastin and Collagen increase more than 300% and 200%, respectively.
1) Gene expression (After 72 hours)
2) Protein expression (After 72 hours)
7.3% increase in skin thickness
23.4% increase in skin elasticity
12.5% increase in skin density
14.3% increase in skin moisture
Dermal Layer Total Care Technology
- Induce Elastin and Collagen synthesis
- Supply Hyaluronic Acids
- Activate cross-linking enzymes